Approximately 350,000 adults in the US experience an out-of-hospital cardiac arrest (OHCA).  Despite numerous potential improvements in treatments, survival from OHCA remains essentially unchanged since 2012. The American Heart Association (AHA) just released its 2020 Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.  In this podcast, we review the key updates and recommendations that impact the acute care provider managing the patient in cardiac arrest.