The TTM2 Trial

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Current international guidelines recommend TTM for adult patients with ROSC from OHCA who remain comatose or unable to follow verbal commands.  However, the overall level of evidence for this recommendation remains of low certainty.  In this podcast, we discuss the results of the recently published TTM2 Trial and its implications on the management of post-cardiac arrest patients.

Early ED Sepsis Care

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Over 80% of patients with sepsis receive care in the ED.  Despite evidence demonstrating the benefits of ED sepsis resuscitation, there remains significant controversies on many aspects of ED sepsis care.  In this podcast, we are joined by EM/CCM extraordinaire Dr. Gabe Wardi, who discuss an upcoming article on ED sepsis resuscitation that will have a significant impact the care …

ECMO for Cardiac Arrest and Massive PE

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Despite continued advances in resuscitation, favorable outcomes for patients with OHCA who receive standard resuscitation remain dismal.  In recent years there has been significant interest in the use of ECMO for OHCA.  However, the evidence demonstrating the efficacy of ECMO in OHCA remains limited.  In this podcast we review the recent ARREST Trial, which evaluated ECMO-facilitated resuscitation in OHCA.  In …

The HOT-ICU Study

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Critically ill patients with acute hypoxic respiratory failure receive supplemental oxygen as a component of their treatment.  In recent years, exposure to high levels of FiO2 with resultant “hyperoxia” have been associated with increased mortality in critically ill patients.  At present, there is no clinical practice guideline on oxygenation targets for adult patients with hypoxic respiratory failure.  In this podcast, we discuss the …

2020 – A Year in Review

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To say that 2020 has been a challenging year would be a gross understatement.  The courage and determination that all healthcare providers have shown in confronting the COVID-19 pandemic has been nothing short of inspirational.  In addition to the thousands of COVID-19 patients, we have also needed to manage many other critical illness conditions that have presented to our various settings.  In this annual …