The BaSICS Trial – Implications for Fluid Resuscitation

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The administration of IVFs is nearly universal in critically ill patients.  In recent years, several studies have suggested improved outcomes with the use of balanced crystalloids solutions in contrast to 0.9% NS.  In this podcast, we discuss the recently published BaSICS Trial that evaluated Plasma-Lyte 148 with 0.9% NS in critically ill patients.  Does this study provide practice-changing evidence to …

The TTM2 Trial

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Current international guidelines recommend TTM for adult patients with ROSC from OHCA who remain comatose or unable to follow verbal commands.  However, the overall level of evidence for this recommendation remains of low certainty.  In this podcast, we discuss the results of the recently published TTM2 Trial and its implications on the management of post-cardiac arrest patients.

ECMO for Cardiac Arrest and Massive PE

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Despite continued advances in resuscitation, favorable outcomes for patients with OHCA who receive standard resuscitation remain dismal.  In recent years there has been significant interest in the use of ECMO for OHCA.  However, the evidence demonstrating the efficacy of ECMO in OHCA remains limited.  In this podcast we review the recent ARREST Trial, which evaluated ECMO-facilitated resuscitation in OHCA.  In …

The HOT-ICU Study

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Critically ill patients with acute hypoxic respiratory failure receive supplemental oxygen as a component of their treatment.  In recent years, exposure to high levels of FiO2 with resultant “hyperoxia” have been associated with increased mortality in critically ill patients.  At present, there is no clinical practice guideline on oxygenation targets for adult patients with hypoxic respiratory failure.  In this podcast, we discuss the …

2020 – A Year in Review

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To say that 2020 has been a challenging year would be a gross understatement.  The courage and determination that all healthcare providers have shown in confronting the COVID-19 pandemic has been nothing short of inspirational.  In addition to the thousands of COVID-19 patients, we have also needed to manage many other critical illness conditions that have presented to our various settings.  In this annual …

2020 AHA Updates: Post-Arrest Care

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The period following ROSC from cardiac arrest is a time when lives can be saved…or lost.  A systematic and comprehensive approach to post-arrest care is associated with improved survival to discharge with good neurologic function.  In this podcast, we discuss the recently published 2020 AHA Updates to Cardiopulmonary Resuscitation and Emergency Cardiovascular Care with attention to Post-Arrest care.